Biotinidase deficiency is a rare autosomal recessive neurometabolic disorder resulting in biotin deficiency.Our patient Brush presented with seizures and developmental delay since infancy and was started on megavitamin supplements.At 14 years, she presented with motor regression with encephalopathy after discontinuation of vitamins.There were no sk
Music is among all cultures an important part of the live of most people.Music has psychological benefits and may generate strong emotional and physiological responses.Recently, neuroscientists have discovered that music influences the reward circuit of the Nicotine Gum nucleus accumbens, even when no explicit reward is present.In this clinical cas
Concretes with water to cement (or binder) ratios of 0.50.0.40, 0.30 and 0.20 were prepared and long-term mechanical properties were measured.Porous light-weight aggregates (LWA) in dosages of 10 % and 20 % were used for self-curing (internal curing) as a partial replacement of fine aggregates for some Brush concrete types.Two environmental conditi
Pre-performance routines (PPRs) can be used in certain sports to minimize the Thermometer effects of choking under pressure.This study aimed to investigate the cumulative effectiveness of PPR interventions on the accuracy of beach volleyball serves.Fifty-four beach volleyball players were randomly assigned to one of three PPR intervention groups or
ABSTRACT The evolution of phage resistance poses an inevitable threat to the efficacy of phage therapy.The strategic selection of phage combinations that impose high genetic barriers to resistance and/or high compensatory fitness costs may mitigate this threat.However, for such a strategy to Brush be effective, the evolution of phage resistance mus